About the Project
Tropical theileriosis is a major tick-borne haemoparasitic disease of cattle and is caused by the protozoan parasite Theileria annulata. The disease is widespread across the Mediterranean basin, Asia Minor, and southern Asia with large cattle populations at risk. In North Africa, the disease has a devastating impact on small-holder farmers, which represent the majority of livestock owners. Recent reports from southern Europe show an increased risk of disease outbreaks in coming years, if the disease remains neglected. On a global basis, the economic impact of tick-borne diseases is immense and enhanced control measures would improve livestock production in many parts of the world.
Currently, management of tropical theileriosis is based on four strategies: control of the tick vector, treatment of infected animals, cell line vaccination and the use of disease resistant breeds. These methods, however, suffer from various drawbacks. Much basic research has been undertaken on the molecular epidemiology, cell biology and immunology of T. annulata. However, a current challenge, which this project aims to address, is re-focusing research efforts towards translational goals, such as improved vaccines, treatments and policy innovations to meet the goals of food security, food safety, alleviation of the poverty, animal welfare and environmental sustainability. The objectives of this project are two-fold: 1) to reduce the impact of the disease on small-holder farmers and 2) to improve quality of life in poor rural communities by improving knowledge and providing access to sustainable, region-specific control strategies.
The project brings together a multi-disciplinary group of experts to study the genetics, immunology and epidemiology of T. annulata and vector ticks. The project will promote collaboration between European and African scientists through addressing questions of joint interest. Sustainable improvement of disease control measures emerging from this project will improve income generation, enhance the economic cooperation between EU and African countries and will promote the competitiveness of African agricultural markets.
